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KMID : 1101020240490010022
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Journal of Oral Medicine and Pain
2024 Volume.49 No. 1 p.22 ~ p.27
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Mucosa-Associated Lymphoid Tissue Lymphoma of the Labial Minor Salivary Glands: Case Report
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Lee Jung-Eun
Han Da-Wool
Kim Hyun-Sil
Lee Che-Na
Park Youn-Jung
Kwon Jeong-Seung
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Abstract
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A 74-year-old female presented with a complaint of dry mouth, continuous spontaneous burning sensation in the tongue, and asymptomatic submucosal soft tissue mass on both sides of the lower labial mucosa. She refused to undergo total excision of the mass due to concern about the possibility of complications such as nerve damage because of the large size of the mass. As her clinical features and magnetic resonance imaging indicated the possibility of Sjogren’s syndrome, a biopsy of the minor salivary gland of the right lower lip was performed. Consequently, she was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma. Although the patient had typical signs and symptoms of Sjogren’s syndrome, the histopathological result of MALT lymphoma made it impossible to determine whether the patient had a history of Sjogren’s syndrome. For patients with risk factors for MALT lymphoma, such as Sjogren’s syndrome, a biopsy of the labial minor salivary gland with immunohistochemical staining can be helpful in the diagnosis of not only Sjogren’s syndrome but also MALT lymphoma.
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KEYWORD
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B-cell, Immunohistochemistry, Lymphoma, Marginal zone, Salivary gland diseases, Sjogren’s syndrome
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